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DOI: 10.66715/cerebral/2026.pmgp | 2026 | Volume 1 | Issue 1 | Page 1-423 | ISBN: 978-81-689463-1-6 | Textbook of Clinical Medicine: Evidence-Based Principles, Diagnosis, and Patient Care | Chapter-12: Preventive Medicine, Geriatrics, Palliative Care, and Future Directions in Clinical Medicine Author:- Dr. Geeta Gill, Associate Professor, Department of Physiotherapy, MM Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed to be University), Mullana

Dr. Manoj Kumar, CEO, SSS Foundation, East Champaran Abstract Background: Infectious diseases remain a major global health challenge, contributing significantly to morbidity, mortality, and healthcare burden despite advances in vaccination, antimicrobial therapy, and public health interventions. Emerging and re-emerging infections, antimicrobial resistance (AMR), sepsis, and critical illness continue to threaten healthcare systems worldwide. Immunological mechanisms play a pi